Radiation biophysics and Radiobiology

The Radiation biophysics and Radiobiology group (RadBioPhys) carries on theoretical and experimental research on ionizing radiation-induced mechanisms and effects on biological structures: from physical interactions (radiation transport and tracks, with Monte Carlo simulations) to biological damage at the sub-cellular (e.g. DNA damage and repair) and cellular (e.g. single-cell or cell-population effects and cell-communication) scales, up to the study of effects at the tissue/organ level (e.g. cancer and non-cancer effects).

Research activities include radiobiological measurements ( RadBioPhys Laboratory ) on 2D and 3D in vitro cellular systems and ex vivo samples, data analysis (including bioinformatic approaches for -omics data), and the development of computational models with a multiscale approach.

Applications range from radiotherapy (for example, to optimize the efficacy of combined treatments, with chemotherapy drugs or immunotherapy) to radiation protection (in particular for the effects of low doses and radiation in human space exploration).

The activities are funded by European and national projects (Italian Space Agency, INFN), and carried out also in collaboration with other UniPv Departments (Molecular Medicine) and IRCCS (San Matteo, Maugeri).

For more information: here.

Local responsible: Giorgio Baiocco 

Group Members: Giorgio Baiocco, Isabella Guardamagna, Alice Mentana, Leonardo Lonati, Géraldine Gonon, Cecilia Riani